Eczane Hizmetleri

Eczane Hizmetleri
Anasayfa Akademik Faaliyetlerimiz
AKADEMİK FAALİYETLERİMİZ


Akademik Faaliyetlerimiz
18 Mayıs 2024 Cumartesi

2023 (18Scopus Indexed Publications)

  1. Congur, G. Electrochemical Biosensors for Monitoring of Drug-DNA Interactions (2023) Current Topics in Medicinal Chemistry, 23 (4), pp. 316-330. DOI: 10.2174/1568026623666230120113550

  2. Congur, G. Current Trends in the Development of Electrochemical Sensors and Biosensors for Biomolecule Analysis (Part II) (2023) Current Topics in Medicinal Chemistry, 23 (15), p. 1425. DOI: 10.2174/156802662315230707112740

  3. Congur, G. Current Trends in the Development of Electrochemical Sensors and Biosensors for Biomolecule Analysis (Part I) (2023) Current Topics in Medicinal Chemistry, 23 (4), p. 283. DOI: 10.2174/156802662304230217154140

  4. Congur, G. An up-to-date review about (bio)sensor systems developed for detection of glyphosate (2023) International Journal of Environmental Analytical Chemistry, 103 (17), pp. 5974-5986. DOI: 10.1080/03067319.2021.1950149

  5. Congur, G., Erdem, A. Development of a Disposable Aptasensor Using Carboxymethyl Cellulose and Hydroxyapatite Nanoparticles for Voltammetric Detection of Glyphosate (2023) Journal of the Electrochemical Society, 170 (5), art. no. 056508 DOI: 10.1149/1945-7111/acd2ff

  6. AL-Sharabi, A.A., Saffour, S., Evren, A.E., Bayazıt, G., Çongur, G., Gül, Ü.D., Yurttaş, L. Synthesis, antimicrobial activity, electrochemical studies and molecular modeling studies of novel 1,3,4-oxadiazole derivatives (2023) Journal of Molecular Structure, 1289, art. no. 135775. DOI: 10.1016/j.molstruc.2023.135775

  7. Özcan S., Geven A., Kozanli M., Can N.Ö. The Development and Full Validation of a Novel Liquid Chromatography Electrochemical Detection Method for Simultaneous Determination of Nine Catecholamines in Rat Brain (2023) Turkish Journal of Pharmaceutical Sciences, 20 (5), pp. 318 – 327 DOI: 10.4274/tjps.galenos.2022.06606

  8. AL-Sharabi, A.A., Evren, A.E., Sağlık, B.N., Yurttaş, L. Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer’s disease (2023) Journal of Biomolecular Structure and Dynamics DOI: 10.1080/07391102.2023.2274967

  9. Osmaniye, D., Evren, A.E., Karaca, Ş., Özkay, Y., Kaplancıklı, Z.A. Novel thiadiazol derivatives; design, synthesis, biological activity, molecular docking and molecular dynamics(2023) Journal of Molecular Structure, 1272, art. no. 134171 DOI: 10.1016/j.molstruc.2022.134171

  10. Yurttaş, L., Evren, A.E., AlChaib, H., Temel, H.E., Akalin Çiftçi, G. Synthesis, molecular docking, and molecular dynamic simulation studies of new 1,3,4-thiadiazole derivatives as potential apoptosis inducers in A549 lung cancer cell line (2023) Journal of Biomolecular Structure and Dynamics DOI: 10.1080/07391102.2023.2300125

  11. Yurttaş, L., Evren, A.E., Kubilay, A., Aksoy, M.O., Temel, H.E., Akalın Çiftçi, G. Synthesis of Some New 1,3,4-Oxadiazole Derivatives and Evaluation of Their Anticancer Activity (2023) ACS Omega, 8 (51), pp. 49311-49326. DOI: 10.1021/acsomega.3c07776

  12. Naji, S.A., Sağlik, B.N., Agamennone, M., Evren, A.E., Gundogdu-Karaburun, N., Karaburun, A.C. Design and Evaluation of Synthesized Pyrrole Derivatives as Dual COX-1 and COX-2 Inhibitors Using FB-QSAR Approach (2023) ACS Omega, 8 (51), pp. 48884-48903. DOI: 10.1021/acsomega.3c06344

  13. Dawbaa, S., Nuha, D., Evren, A.E., Cankiliç, M.Y., Yurttaş, L., Turan, G. New oxadiazole/triazole derivatives with antimicrobial and antioxidant properties (2023) Journal of Molecular Structure, 1282, art. no. 135213 DOI: 10.1016/j.molstruc.2023.135213

  14. Evren, A.E., Nuha, D., Dawbaa, S., Karaduman, A.B., Sağlik, B.N., Yurttaş, L. Novel oxadiazole-thiadiazole derivatives: synthesis, biological evaluation, and in silico studies (2023) Journal of Biomolecular Structure and Dynamics DOI: 10.1080/07391102.2023.2247087

  15. Nuha, D., Evren, A.E., Kapusiz, Ö., Gül, Ü.D., Gundogdu-Karaburun, N., Karaburun, A.Ç., Berber, H. Design, synthesis, and antimicrobial activity of novel coumarin derivatives: An in-silico and in-vitro study (2023) Journal of Molecular Structure, 1272, art. no. 134166 DOI: 10.1016/j.molstruc.2022.134166

  16. Ultav, G., Tonbul, H., Sahin, A., Capan, Y. Silica nanoparticle synthesis by experimental design for drug and gene delivery applications (2023) Journal of Research in Pharmacy, 27 (1), pp. 012-022. DOI: 10.29228/jrp.243

  17. Şahin, A., Çilingiroğlu, G.Y., Çatak, T., Ulusoy, S., Gül, Ü.D., Gündoğdu, S.Ö. Comparative evaluation of lyophilized voriconazole formulations marketed in European Union (2023) Journal of Research in Pharmacy, 27 (1), pp. 120-129. DOI: 10.29228/jrp.297

  18. Anthiya, S., Öztürk, S.C., Yanik, H., Tavukcuoglu, E., Şahin, A., Datta, D., Charisse, K., Álvarez, D.M., Loza, M.I., Calvo, A., Sulheim, E., Loevenich, S., Klinkenberg, G., Schmid, R., Manoharan, M., Esendağlı, G., Alonso, M.J. Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors (2023) Journal of Controlled Release, 357, pp. 67-83. DOI: 10.1016/j.jconrel.2023.03.016

 

2022 (16 Scopus Indexed Publications)

1- Congur, G., Gül, I.D., Taştan, B.E. Fast, Cheap and Reliable Monitoring of Microalgae-Based Paracetamol Removal from Aquatic Environment Using Electrochemical Sensor Technology (2022) 169 (11), art. no. 115503.DOI: 10.1149/1945-7111/aca0c8

2- Congur, G., Gül, Ü.D. Electrochemical Detection of Phenol Removal by Using a Biosorbent Originated Factory Solid Waste (2022) 34 (3), pp. 455-463. DOI: 10.1002/elan.202100520

3- Saǧllk, B.N., Levent, S., Osmaniye, D., Evren, A.E., Karaduman, A.B., Özkay, Y., Kaplanclkll, Z.A. Design, Synthesis, and in Vitro and in Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents (2022) 7 (50), pp. 47378-47404. DOI: 10.1021/acsomega.2c06906

4- Dawbaa, S., Evren, A.E., Sağlik, B.N., Gundogdu-Karaburun, N., Karaburun, A.C. Biological activity evaluation of novel monoamine oxidase inhibitory compounds targeting Parkinson disease (2022) 14 (22), pp. 1663-1679. DOI: 10.4155/fmc-2022-0167

5- Durmaz, Ş., Evren, A.E., Sağlık, B.N., Yurttaş, L., Tay, N.F. Synthesis, anticholinesterase activity, molecular docking, and molecular dynamic simulation studies of 1,3,4-oxadiazole derivatives (2022) 355 (11), art. no. 2200294. DOI: 10.1002/ardp.202200294

6- Nuha, D., Evren, A.E., Çiyanci, Z.Ş., Temel, H.E., Akalin Çiftçi, G., Yurttaş, L. Synthesis, density functional theory calculation, molecular docking studies, and evaluation of novel 5-nitrothiophene derivatives for anticancer activity (2022) 355 (9), art. no. 2200105, . DOI: 10.1002/ardp.202200105

7- Turan Yücel, N., Evren, A.E., Kandemir, Ü., Can, Ö.D. Antidepressant-like effect of tofisopam in mice: A behavioural, molecular docking and MD simulation study (2022) 36 (7), pp. 819-835. DOI: 10.1177/02698811221095528

8- Osmaniye, D., Evren, A.E., Sağlık, B.N., Levent, S., Özkay, Y., Kaplancıklı, Z.A. Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO-B dual inhibitors (2022) 355 (3), art. no. 2100450, . DOI: 10.1002/ardp.202100450

9- Evren, A.E., Nuha, D., Dawbaa, S., Sağlık, B.N., Yurttaş, L. Synthesis of novel thiazolyl hydrazone derivatives as potent dual monoamine oxidase-aromatase inhibitors (2022) 229, art. no. 114097. DOI: 10.1016/j.ejmech.2021.114097

10- Acar Çevik, U., Işık, A., Evren, A.E., Kapusız, Ö., Gül, Ü.D., Özkay, Y., Kaplancıklı, Z.A. Synthesis of new benzimidazole derivatives containing 1,3,4-thiadiazole: their in vitro antimicrobial, in silico molecular docking and molecular dynamic simulations studies (2022) 33 (11), pp. 899-914. DOI: 10.1080/1062936X.2022.2149620

11- Evren, A.E., Yurttaş, L., Gencer, H.K. Synthesis of New Thiazole Derivatives Bearing Thiazolidin-4(5H)-One Structure and Evaluation of Their Antimicrobial Activity (2022) 58, art. no. e19248. DOI: 10.1590/s2175-97902022e19248

12- Sahin, A., Ozturk, S.C. Intraperitoneal administration of PLGA nanoparticles could deliver the cargo to tumor-associated macrophages with less spreading peritoneal macrophages in the treatment of peritoneal carcinomatosis (2022) 77, art. no. 103829, . DOI: 10.1016/j.jddst.2022.103829

13- Cetin, N., Menevse, E., Celik, Z.E., Ceylan, C., Rama, S.T., Gultekin, Y., Tekin, T., Sahin, A. Evaluation of burn wound healing activity of thermosensitive gel and PLGA nanoparticle formulation of quercetin in Wistar albino rats (2022) 75, art. no. 103620, . DOI: 10.1016/j.jddst.2022.103620

14- Ultav, G., Tonbul, H., Tavukcuoglu, E., Ozturk, S.C., Akbas, S., Sahin, A., Esendagli, G., Capan, Y. pH-sensitive chitosan-PEG-decorated hollow mesoporous silica nanoparticles could be an effective treatment for acute myeloid leukemia (AML) (2022) 24 (2), art. no. 40, . DOI: 10.1007/s11051-022-05404-8

15- Tonbul, H., Şahin, A., Çapan, Y. Overcoming the challenges of drug resistance through combination drug delivery approach (2022) pp. 31-46. DOI: 10.1016/B978-0-323-85873-1.00003-4

16- Gultekin, Y., Tekin, T., Kocas, M., Capan, Y., Sahin, A. PLGA-Based Nanomaterials for Cancer Therapy (2022) pp. 263-284.

2021 (19 Scopus Indexed Publications)

1- Gül, U.D., Congur, G., Yavuz, Ş.A.  Single-Use Electrochemical Platform for Monitoring of Antimicrobial Activity in Comparison to Minimum Inhibitory Concentration Assay (2021) 168 (8), art. no. 087505. DOI: 10.1149/1945-7111/ac1893

2- Özcan S., Levent S., Can N.Ö., Kozanli M.  A novel hplc method for simultaneous determination of methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl and benzyl paraben in pharmaceuticals and cosmetics (2021), 24 (3), pp. 352 - 365 DOI: 10.2174/1386207323999200728121657

3- Congur, G. Development of a novel methyl germanane modified disposable sensor and its application for voltammetric phenol detection (2021) 25, art. no. 101268, . DOI: 10.1016/j.surfin.2021.101268

4- Congur, G.Monitoring of glyphosate-DNA interaction and synergistic genotoxic effect of glyphosate and 2,4-dichlorophenoxyacetic acid using an electrochemical biosensor (2021) 271, art. no. 116360. DOI: 10.1016/j.envpol.2020.116360

5- Congur, G. An up-to-date review about (bio)sensor systems developed for detection of glyphosate (2021) . DOI: 10.1080/03067319.2021.1950149

6- CONGUR, G. Electrochemical investigation of the interaction of 2,4-D and double stranded DNA using pencil graphite electrodes (2021) 45 (3), pp. 600-615. DOI: 10.3906/kim-2011-56

7- Congur, G., Eksin, E., Erdem, A. Levan modified DNA biosensor for voltammetric detection of daunorubicin-DNA interaction (2021) 326, art. no. 128818, . DOI: 10.1016/j.snb.2020.128818

8- EVREN, A.E., DAWBAA, S., NUHA, D., YAVUZ, Ş.A., GÜL, Ü.D., YURTTAŞ, L. Design and synthesis of new 4-methylthiazole derivatives: In vitro and in silico studies of antimicrobial activity (2021) 1241, art. no. 130692. DOI: 10.1016/j.molstruc.2021.130692

9- Ateş, I.O., Evren, A.E., Saǧlik, B.N., Yurttaş, L New indane derivatives containing 2-hydrazinothiazole as potential acetylcholinesterase and monoamine oxidase-B inhibitors (2021) 76 (9-10), pp. 417-424. DOI: 10.1515/znc-2021-0.

10- Yücel, N.T., Osmaniye, D., Kandemir, Ü., Evren, A.E., Can, Ö.D., Özkay, Ü.D. Synthesis and antinociceptive effect of some thiazole-piperazine derivatives: Involvement of opioidergic system in the activity (2021) 26 (11), art. no. 3350, . DOI: 10.3390/molecules26113350

11- Dawbaa, S., Evren, A.E., Cantürk, Z., Yurttaş, L. Synthesis of new thiazole derivatives and evaluation of their antimicrobial and cytotoxic activities (2021) 196 (12), pp. 1093-1102. DOI: 10.1080/10426507.2021.1972299

12- Nuha, D., Evren, A.E., Yılmaz Cankılıç, M., Yurttaş, L. Design and synthesis of novel 2,4,5-thiazole derivatives as 6-APA mimics and antimicrobial activity evaluation (2021) 196 (10), pp. 954-960. DOI: 10.1080/10426507.2021.194653

13- Yurttaş, L., Evren, A.E., Kubilay, A., Temel, H.E. Synthesis of new 1,2,4-triazole derivatives and investigation of their matrix metalloproteinase-9 (Mmp-9) inhibition properties (2021) 59 (2), pp. 215-232. DOI: 10.23893/1307-2080.APS.05913

14- Evren, A.E., Yurttaş, L., Ekselli, B., Aksoy, O., Akalin-çiftçi, G. Design and efficient synthesis of novel 4,5-dimethylthiazole-hydrazone derivatives and their anticancer activity

(2021) 18 (4), pp. 372-386. DOI: 10.2174/1570180817999201022192937

15- Seko, I., Tonbul, H., Tavukçuoğlu, E., Şahin, A., Akbas, S., Yanık, H., Öztürk, S.C., Esendagli, G., Khan, M., Capan, Y. Development of curcumin and docetaxel co-loaded actively targeted PLGA nanoparticles to overcome blood brain barrier (2021) 66, art. no. 102867, . DOI: 10.1016/j.jddst.2021.102867

16- Tonbul, H., Sahin, A., Tavukcuoglu, E., Ultav, G., Akbas, S., Aktas, Y., Esendaglı, G., Capan, Y. Folic acid decoration of mesoporous silica nanoparticles to increase cellular uptake and cytotoxic activity of doxorubicin in human breast cancer cells (2021) 63, art. no. 102535, . DOI: 10.1016/j.jddst.2021.102535

17- Çetintaş, H.C., Tonbul, H., Şahin, A., Çapan, Y. Regulatory Guidelines of the US Food and Drug Administration and the European Medicines Agency for Actively Targeted Nanomedicines (2021) pp. 725-741. DOI: 10.1201/9781003164739-27

18- Sahin, A., Ceylan, C., Ertan-Ahmed, S. Clinical Trials of Targeted Nanoparticulate Drug Delivery Systems (2021) pp. 615-642. DOI: 10.1201/9781003164739-22

19-Çapan, Y., Sahin, A., Tonbul, H. Drug Delivery with Targeted Nanoparticles: In Vitro and in Vivo Evaluation Methods (2021) pp. 1-761. DOI: 10.1201/9781003164739